Proteomics and Disease (379-0-1)

Instructors

John Mordacq
8474917835
Tech MG79, 2145 Sheridan

Meeting Info

Technological Institute MG78: Mon, Wed, Fri 10:00AM - 10:50AM

Overview of class

This course is designed to investigate the homeostasis of the proteome, what mechanisms maintain this homeostasis, and how breakdown of these mechanisms leads to disease. The topics will cover gene expression, the biochemistry of protein folding, and the various pathways that ensure proper protein folding as well as the destruction of misfolded proteins and aggregates. The topics covered will be a progression of the material learned in NU's introductory biology courses.

Learning Objectives

At the end of this course students should be able to read, interpret and discuss primary research articles, define key terminology, have an enhanced grasp of concepts learned in previous courses (translation, protein folding, mutations, and structure/function relationships), describe the processes within a cell that maintain proteomic homeostasis, and explain the relationship between breakdown of homeostatic mechanisms and the disease state.

Teaching Method

lecture, problem sets, multiple forms of assessment such as quizzes and exams.

Class Materials (Required)

No required textbook

Enrollment Requirements

Enrollment Requirements: Prerequisites: BIOL_SCI 203-0, BIOL_SCI 234-0, and BIOL_SCI 301-0.