Organometallic Reaction Mechanisms (412-0-01)

Instructors

Sonbinh T Nguyen

Meeting Info

Technological Institute M128: Tues, Thurs 9:30AM - 10:50AM

Overview of class

Elucidation of organic and organometallic reaction mechanisms: experiment, theory, and selected case studies.

By the end of the course, students should be able to:

-Identify reasonable reaction pathways for organic and organometallic transformations.
-Qualitatively interpret potential energy surfaces.
-Derive rate laws for multistep reactions, including catalytic reactions.
-Have familiarity with the tools of mechanistic analysis, including kinetic analysis, linear free energy relationships, isotopic labeling, Eyring analysis,
competition experiments, crossover experiments, radical clocks, and use of stereochemical information.
-Identify experiments that would allow the differentiation of possible reaction mechanisms.
-Search and read the primary literature.
-Orally summarize and critically analyze journal articles.
-Write about reaction mechanism with clarity and precision.

Registration Requirements

Full year of organic chemistry or by permission of the instructor.

Class Materials (Required)

Title: The Organometallic Chemistry of the Transition Metals, 7th ed.
Author: Crabtree
Publisher: Wiley
ISBN: 9781119465867
Approx. price: $123 new, $61 used rental