Organometallic Reaction Mechanisms (412-0-20)

Instructors

Sonbinh T Nguyen

Meeting Info

Technological Institute M177: Tues, Thurs 9:30AM - 10:50AM

Overview of class

Elucidation of organic and organometallic reaction mechanisms: experiment, theory, and selected case studies.

By the end of the course, students should be able to:

-Identify reasonable reaction pathways for organic and organometallic transformations.
-Qualitatively interpret potential energy surfaces.
-Derive rate laws for multistep reactions, including catalytic reactions.
-Have familiarity with the tools of mechanistic analysis, including kinetic analysis, linear free energy relationships, isotopic labeling, Eyring analysis,
competition experiments, crossover experiments, radical clocks, and use of stereochemical information.
-Identify experiments that would allow the differentiation of possible reaction mechanisms.
-Search and read the primary literature.
-Orally summarize and critically analyze journal articles.
-Write about reaction mechanism with clarity and precision.

Registration Requirements

Full year of organic chemistry or by permission of the instructor.

Registration in this class is restricted to graduate students in the Chemistry Department. Other students may register with department permission.

Class Materials (Required)

Title: The Organometallic Chemistry of the Transition Metals, 7th ed.
Author: Crabtree
Publisher: Wiley
ISBN: 9781119465867
Approx. price: $119 new, $55 rental

Enrollment Requirements

Enrollment Requirements: Registration in this class is restricted to graduate students in the Chemistry Department. Other students may register with department permission.